KEGG   Sus scrofa (pig): 396857
Entry
396857            CDS       T01009                                 
Symbol
DDC
Name
(RefSeq) aromatic-L-amino-acid decarboxylase isoform X1
  KO
K01593  aromatic-L-amino-acid/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]
Organism
ssc  Sus scrofa (pig)
Pathway
ssc00350  Tyrosine metabolism
ssc00360  Phenylalanine metabolism
ssc00380  Tryptophan metabolism
ssc01100  Metabolic pathways
ssc04726  Serotonergic synapse
ssc04728  Dopaminergic synapse
ssc05030  Cocaine addiction
ssc05031  Amphetamine addiction
ssc05034  Alcoholism
Module
ssc_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
ssc_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:ssc00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    396857 (DDC)
   00360 Phenylalanine metabolism
    396857 (DDC)
   00380 Tryptophan metabolism
    396857 (DDC)
 09150 Organismal Systems
  09156 Nervous system
   04728 Dopaminergic synapse
    396857 (DDC)
   04726 Serotonergic synapse
    396857 (DDC)
 09160 Human Diseases
  09165 Substance dependence
   05030 Cocaine addiction
    396857 (DDC)
   05031 Amphetamine addiction
    396857 (DDC)
   05034 Alcoholism
    396857 (DDC)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ssc04147]
    396857 (DDC)
Enzymes [BR:ssc01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.28  aromatic-L-amino-acid decarboxylase
     396857 (DDC)
    4.1.1.105  L-tryptophan decarboxylase
     396857 (DDC)
Exosome [BR:ssc04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   396857 (DDC)
SSDB
Motif
Pfam: Pyridoxal_deC Beta_elim_lyase Aminotran_1_2
Other DBs
NCBI-GeneID: 396857
NCBI-ProteinID: XP_020919586
Position
9:complement(136496364..136571220)
AA seq 486 aa
MNASDFRRRGKEMVDYMADYLEGIEGRQVYPDVQPGYLRPLIPATAPQEPDTFEDILQDV
EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
WLGKMLQLPEAFLAGEAGEGGGVIQGSASEATLVALLAARTKVTRRLQAASPGLTQGAVL
EKLVAYASDQAHSSVERAGLIGGVKLKAIPSDGKFAMRASALQEALERDKAAGLIPFFVV
ATLGTTSCCSFDNLLEVGPICHEEDIWLHVDAAYAGSAFICPEFRHLLNGVEFADSFNFN
PHKWLLVNFDCSAMWVKRRTDLTGAFKLDPVYLKHSHQGSGLITDYRHWQLPLGRRFRSL
KMWFVFRMYGVKGLQAYIRKHVQLSHEFEAFVLQDPRFEVCAEVTLGLVCFRLKGSDGLN
EALLERINSARKIHLVPCRLRGQFVLRFAICSRKVESGHVRLAWEHIRGLAAELLAAEEG
KAEIKS
NT seq 1461 nt   +upstreamnt  +downstreamnt
atgaatgcaagcgacttccgccggcgggggaaggagatggtggattacatggctgactac
ctggagggcatcgagggtcgccaggtgtatcccgacgtgcagcccggctacctgcgcccc
ctgatccccgccaccgccccccaggagccagacacgtttgaggacatccttcaggacgtt
gagaagataatcatgccgggggtgacccactggcacagcccctacttcttcgcctacttc
cccacggccagctcgtacccggccatgctcgccgacatgctgtgtggggccattggctgc
atcggcttctcctgggctgccagcccggcatgcacggagctggagacagtgatgatggac
tggctggggaagatgctgcagctgcccgaggcgtttctggctggagaggccggagaaggc
ggcggggtgatccagggaagtgccagtgaagctaccttggtggccctgctggctgctcgg
accaaagtgacgcgacgcctgcaggccgcctccccggggctgacccaaggggccgtcttg
gagaagctggtggcctatgcatccgaccaggcacactcctcggtggaaagagccggcttg
attggtggcgtgaaattaaaagcaatcccttcggatggcaagtttgccatgcgagcttct
gccctgcaggaggccctggagagagacaaggctgccggcctgattcctttcttcgtggtg
gctacgctggggaccacatcgtgctgctcctttgacaatctcttagaagtgggacccatc
tgtcacgaagaggacatatggctgcacgtggatgctgcctacgcaggcagtgccttcatc
tgccctgagttccggcacctgctgaatggagtggagtttgcagattcatttaactttaat
ccccacaaatggctcttggtgaattttgactgctcggctatgtgggtgaaaaggagaacg
gacctgactggagccttcaaattggaccccgtgtacttaaagcacagccaccagggctcg
gggcttatcacggactacaggcactggcagctgccactgggtcggcgattccggtccctg
aaaatgtggtttgttttcaggatgtacggagtcaagggactgcaggcctatatccgcaag
cacgtgcagctgtctcatgagtttgaggcatttgtgcttcaggatccccgctttgaagtc
tgtgccgaagtcaccctggggctggtgtgtttccggctgaagggctccgacggactgaat
gaagcgcttctggaaaggataaacagcgccaggaaaatccacttggttccctgtcgcctg
aggggccagttcgtgctgcggttcgccatctgctcgcgcaaggtggagtcgggccacgtg
cggctggcctgggagcacatccgagggctggcggccgagctgctggccgcggaggaggga
aaggcagagatcaaaagttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (9)   
   KEGG MODULE (3)   
Chemical substance (13)   
   KEGG COMPOUND (13)   
Chemical reaction (8)   
   KEGG ENZYME (2)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (21)   
   RefSeq(nuc) (5)   
   GenBank (8)   
   EMBL (8)   
Protein domain (3)   
   Pfam (3)   
All databases (73)   

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